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Additionally, in microglia, LRRK2 exerts a negative regulatory effect on -syn clearance by downregulating the early endocytosis pathway, as LRRK2 -knockout microglia exhibit enhanced -syn uptake and clearance associated with increased Rab5-positive early endosomes and improved Rab5-dynamin 1 coordination (195)

You may take more than a serving, based on your own tolerance

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Gao Y, Kong F, Song X, Shang J, Yao L, Xia J, Peng Y, Liu W, Gong H, Mu M, Cui H, Han T, Chen W, Wu X, Yang Y, Yan X, Jin Z, Wang P, Zhu Q, Chen L, Zhao C, Zhang D, Jin W, Wang D, Wen X, Liu C, Jia J, Mao Q, Ding Y, Jin X, Zhang Z, Mao Q, Li G, Niu J