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[PubMed abstract] Yeung LF, Cogswell ME, Carriquiry AL, et al

PRDXs and chemoresistance Cancer cells, compared with normal cells, have a high rate of ROS production as by-products of their metabolism (152), and to survive with this redox status, the levels of antioxidant proteins, such as CAT, SOD, glutaredoxin and PRDXs, are increased (152154)

2023c;115:109731

Most of the amino groups derived from glutamate enter the urea cycle, whereas a smaller fraction may serve as nitrogen donors in biosynthetic reactions