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2024 Feb 16;15:1272084

In addition, TNF- induces the expression of PDK1 via PI3K/Akt-HIF-1 in bFLS 24 and thus might interfere with pyruvate mitochondrial utilization through the TCA cycle 53

In the future, the regulatory field around peptides may partly mirror the regulation of dietary supplements: they are regulated, but their safety must be supported by evidence of no harm, and promises about outcomes must be realistic and tightly tied to available data

However, the results varied because researchers used different wavelengths, light intensities, and session lengths in their studies (Korada et al., 2022)