glutathione biosynthesis inhibitor Combined inhibition of de novo and nucleotide is synthetically lethal in glioblastoma A role for microsomal glutathione

The withdrawal responses elicited by the injection of NLX in rats that had received co-injections of morphine plus vehicle were qualitatively and quantitatively similar in the rats that had received co-injections of morphine plus D-cysteine

1) [91], cell apoptosis and even canceration [58, 102]

Its effects are pathogen-specific (16, 74): necroptosis correlates positively with immune infiltration during influenza infection but has limited impact in bacterial infections, highlighting pathogen-dependent immune regulation

Uzumcu M, Zachow R

In view of the GO results, the Kyoto Encyclopedia of Genes and Genomes (KEGG) network enrichment analysis highlighted a greater effect on a metabolic pathway, glutathione metabolism (path:ko00480), which included upregulated Ggt1 and downregulated Anpep, in OVX rats (Figure 2F, and see Supplementary Tables S7)