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Consequently, A2AR blockade enhances T cell effector function while inducing ferroptosis due to increased lipid peroxidation, which provides a mechanistic explanation for the recent observations of decreased survival of tumor-infiltrating A2AR-deficient T cells (46) or activated CD73-deficient CD8 + T cells under antigenic stimulation (47)

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Microbial control of arthropod pests in small fruits and vegetables in temperate climate in Microbial Control of Insect and Mite Pests

Cancer 127(11):1788-1795, 2021

As such, these findings have therapeutic implications in diseases, such as myocardial infarction and Alzheimers disease, where resident macrophage functions are altered