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Deficiencies and Prospects Currently, diagnostic examinations for PH include right heart catheterization, blood gas analysis, X-ray, computed tomography (CT), and echocardiography

Furthermore, great concern for the evidence suggesting that activation of 7nAChRs through some drugs or herbal medicine may impact brain function and clarify underlying molecular mechanisms, including oxidative stress, inflammation, and apoptosis

The interaction of BIM with anti-apoptotic BCL-2 homologs is especially critical when stress signals promote BIM expression, disturbing the balance between anti- and pro-apoptotic BCL-2 proteins, thereby favoring apoptosis

Statistical analyses were performed by unpaired two-tailed Students t test ( b , d , f , g i )