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Autophagy is a degradation pathway essential for maintaining cellular homeostasis during different stressful conditions

These concepts are schematically illustrated in Figure 2 highlighting how therapy-driven clonal selection can be longitudinally tracked using tissue and liquid biopsy approaches

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Firstly, people with fatty liver disease often have underlying metabolic conditions such as insulin resistance or obesity, and dietary protein intake should be balanced within an overall healthy eating pattern as recommended by NICE and the NHS