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Ganoderma atrum polysaccharide interferes with TLR4 against PD-1 inhibitors-induced carditis via NF-B-NLRP3 pathway driven by IRF1/VEGFA/143-3 axis in lewis lung carcinoma mice

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Hijamat or three-edged needling Three-edged needling in TCM and Hijamat in TPM have the same mechanism based on which the most painful area is selected, and after routine sterilization, the three-edged needle is inserted swiftly and removed immediately for three to five consecutive times around the local area or based on TPM method incised by blade for a small incision of 23 mm (45 incisions for every area), and then put the flare fire cupping for 1015 minutes and allow to bleed for 36 mL [19]