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Since only around 10% of TNBC has FGFR (Fibroblast Growth Factor Receptors) identified as a therapeutic target, pan-FGFR inhibitors such alofanib and PD173074 prevent SUM52PE from proliferating and cause apoptosis by blocking the MAPK and PI3K signalling pathways (65)

The diaphorase enzyme, an oxidoreductase in the mitochondrial respiratory chain, maintains a balance between the oxidized and reduced forms of NADH to sustain sperm motility

it is not suitable for use in diagnostic procedures without further evaluation.

c , Venn diagram of differentially expressed genes in response to treatments