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Given the established role of FXR activation in suppressing lipid peroxidation and the critical importance of granulosa cell integrity for follicular development, BAs may represent important endogenous regulators of ovarian function in PCOS

McGraw-Hill Global Education

Data statistics are shown in Figure 4B

Oligodendrocytes have the highest iron content in the brain (Connor and Menzies, 1996), which may explain their high sensitivity to oxidative stress (Smith et al., 1999)