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Description

2006 Oct;46(10):1163-70

Formononetin, an isoflavone, not only inhibits degranulation of mast cells and basophils but also directly suppresses IgE production by human peripheral blood mononuclear cells through modulation of the JAK/STAT/PI3K-Akt signaling pathway, thereby attenuating allergic responses (127)

Am J Physiol Cell Physiol 287:C327-C335 Breyer J, Samarin J, Rehm M, Lautscham L, Fabry B, Goppelt-Struebe M (2012) Inhibition of Rho kinases increases directional motility of microvascular endothelial cells