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Ind Eng Chem Res

Shintoku R, Takigawa Y, Yamada K, Kubota C, Yoshimoto Y, Takeuchi T, et al

At Month 12, the mean change from baseline in ALP for patients with cirrhosis on seladelpar was -121.4 U/L vs 23.2 U/L for placebo, and -134.8 U/L for seladelpar vs -18.0 U/L for placebo in patients without cirrhosis

These 'stop pathways' also provide clues as to why some individuals become 'problem drinkers' and exhibit phenotypes of alcohol use disorder, whereas the majority of people do not