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References Allison SD, Chang B, Randolph TW, Carpenter JF (1999) Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding

You should avoid processed, sugary, and high-fat items

Activation of sirtuins: Particularly SIRT1 and SIRT3, which are NAD+-dependent deacetylases involved in metabolic regulation and stress resistance 42

faecalis virulence factors (such as CylLL-hemolysin), synergistically exacerbating host cell damage (Kapitan et al., 2025)

This well-established importance underlies the role of vitamin B12 deficiency in mood imbalances, psychotic disorders, and neuronal health, particularly in elderly patients, where this deficiency is estimated to affect up to 40% of the population (72)