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Moreover, loss of DJ-1 impairs microglial function through heightened inflammatory response to -syn, reduced -syn uptake due to lipid raft disruption, and defective autophagy-lysosomal degradation (Nash et al., 2017)

This study suggests that HYSA could serve as a novel therapeutic agent for sepsis, paving the way for further research and development in this field

doi: 10.2165/00003495-198938040-00003 14 BrownE

this is probable given that we did not find any associations between motor performance and frontal GSH levels, and that we found positive correlations between GSH levels across the two voxels

Earlier biguanides such as phenformin and buformin showed greater potency but were withdrawn from the market due to a high incidence of lactic acidosis (LaMoia and Shulman, 2021)