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The FDA's formal evaluation process reviewed AOD-9604 against four statutory criteria: physicochemical characterization, safety, historical use in compounding, and available evidence of effectiveness

Some users report better subjective results with subcutaneous AOD 9604 than the oral formulation used in trials, but controlled data supporting those anecdotal reports does not exist at a level that would change the fundamental comparison

GLP-1 agonists work primarily through appetite suppression and slower gastric emptying

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