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Hardingham GE, Do KQ

Arsenic trioxide enhances the chemotherapeutic efficiency of cisplatin in cholangiocarcinoma cells via inhibiting the 14-3-3-mediated survival mechanism

SVCT1 has consistently been found to have a higher capacity to transport ascorbate (i.e., higher V m ), whereas SVCT2 has a slightly higher affinity for ascorbate, with a K 0.5 of 1070 M versus 20100 M for SVCT1