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Zhang Y, Guo L, Han S, Chen L, Li C, Zhang Z, et al

A study found that by examining the postmortem brain tissue of suicidal patients with depression, the astrocyte-specific methylation map in the genome showed that glutamate receptor ionotropic kainate 2 and brain-rich guanosine kinase-related protein, which are associated with depressive psychopathology, were less methylated 134

In the setting of diabetes, lipid peroxidation and ALE formation has been implicated in the pathogenesis of macro- and microvascular complications

Less Folate means B12 doesnt have a methyl group to pass on and Homocysteine builds up

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