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doi: 10.1126/scitranslmed.aau5516 18 ChaiSSmithCCKocharTKHunsuckerSABeckWOlsenKSet al

This inflammatory process includes microglial activation, increased cytokine release, and increased oxidative stress, as well as changes in glutamatergic system regulation that may exacerbate astrocyte atrophy and local damage following these events (48)