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The intracellular glutamate concentration is nearly 10-fold higher than the Km value, but intracellular cysteine concentrations approximate the apparent Km value [10] , indicating that cysteine may be a limiting substrate for GCL

J Am Chem Soc 128:1281712828 Crespo A, Scherlis DA, Mart MA, Ordejn P, Roitberg AE, Estrin DA (2003) A DFT-based QM-MM approach designed for the treatment of large molecular systems: application to chorismate mutase

The legitimate worry with sustained NNMT inhibition isnt tolerance in the receptor sense

Next time youre about to grab a Rainbow Rocket Unicorn Tea, pause and ask yourself: Do I really need all that or am I just thirsty

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