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doi:10.1177/1535370213477602

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When a leaving group is installed at the propargyl position of COT, this intermediate undergoes rapid 1,4-elimination, releasing the payload and generating a nitroneoctenea bioorthogonal bond-cleavage reaction with fast kinetics and near-quantitative efficiency (Fig

sylvestris extract could be related to its rich make-up of phenolic acids (epicatechic acid, gallic acid, coumaric acid, vanillic acid, and catechic acid) and flavonoids (rutin, kaempferol, quercetin, and luteolin)

Samples were reconstituted in 90 l of 50% acetonitrile (Fisher Scientific, A955) and transferred to glass vials for LCMS analysis