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Dietary supplementation with fresh pineapple juice decreases inflammation and colonic neoplasia in IL-10-deficient mice with colitis

Hypothyroidism Several herbs are identified with their positive role in the management of hypothyroidism

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ACDR can cause a number of blistering eruptions including: A fixed drug eruption (above) Stevens-Johnson syndrome / Toxic epidermal necrolysis (refer above under serious ACDR) Immunobullous reactions - very uncommon Other possible presentations of ACDR: Acneiform ie acne-like Pustular ie white-yellow pustules - pustules can be localised but are more often generalised and known as acute generalized exanthematous pustulosis (AGEP ) Purpura / cutaneous vasculitis - red-purple palpable lesions most commonly on lower legs, which do not blanch on pressure Erythema nodosum (EN) - painful nodules on the shins Erythema multiforme (EM) - those that are secondary to medication tend to cause more varied and less well-defined target lesions than when due to herpes simplex (antibiotics can be an exception) Skin ulceration and infarction - two of the most commonly associated medications that cause ulceration are hydroxyurea and nicorandil

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