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Rao JS, Harry GJ, Rapoport SI, Kim HW

These benefits were associated with mitochondrial phenotypic changes such as upregulated anti-apoptotic proteins, reduced pro-apoptotic proteins and improved mitochondrial biogenesis and fusion (Jang et al., 2018)

Simulation system equilibration and energy minimization Following preparation, the systems were energy minimized with an energy tolerance of 100 kj/mol and equilibrated in six sequential steps involving loosening of positional restraints on lipid atoms, protein backbone atoms, and protein side chain atoms (equilibration parameters in Extended Data Table 2)