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Mitochondria-nucleus interactions: epigenetic regulation and metabolic feedback In ovarian cells, mitochondria-nucleus interactions are crucial for maintaining cellular energy balance, genome stability, and supporting key processes including follicle development, ovulation, and corpus luteum formation

Once it reaches the cytoplasmic compartment, H 2 O 2 contributes to activating the inflammatory cells and triggering the pro-inflammatory pathways (56)

125 Notably, ELISA demonstrate that IDH1 level is also significantly elevated in the plasma of NSCLC patients, suggesting that it can be used as a potential plasma biomarker