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Elevated intracellular ROS levels in spinal cord dorsal neurons induce the activation of the neuronal ferroptosis pathway and participate in the process of NP

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Subgroup analyses stratified by sex revealed no statistically significant differences in total iron levels, TF concentrations, or TF saturation in between males and females within either the control or AMD groups, although slightly higher iron levels were observed in male AMD patients (Supplementary Fig

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Structurally, copper ions can bind to various intracellular proteins, stabilizing their structures