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This article was financially supported by National Institutes of Health Public Health Service grants R01 HL144790, R01 HL151493, R01 AI145813, R01 AI169687, R01 HL151769, and R01 HL159804 (OA)

Lactoferrin shows particularly high transcytosis efficiency, while Angiopep-2 is widely validated in brain-targeted delivery systems

WO 04/014292, WO 03/094859 and U.S

For example, the conjugate may be purified by HPLC using one or more suitable solvents

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