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10.3389/fnins.2022.824888 62 GevezovaM.SbirkovY.SarafianV.PlaimasK.SurataneeA.MaesM

Practical strategies to circumvent the toxicity issues of UCNPs include the fabrication of ultra-small nanoparticles to increase biological elimination, surface functionalization with bio-biocompatible ligands or detoxifying reagents, and enhancement of the upconversion efficiency of UCNPs to decrease light dosage in practice

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doi: 10.1021/bi0258795