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28 mo+AP n=15 mice)

Even if youre pregnant or undergoing treatments like chemotherapy, B12 shots are perfectly safe

Reviews of the rodent work note that the mechanism doesnt involve the hormonal suppression or receptor desensitization that would predict tolerance or rebound, and that adipose SAM levels tend to normalize rather than crash under inhibition

Discontinue use if irritation occurs

However, it has been shown that high blood levels of vitamin B12 can cause the diagnostic features of cobalamin deficiency , which is due to binding to the different transport proteins