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Similar to the CP-induced AKI model, necroptosis inhibitors synergize apoptosis inhibitors to attenuate renal injury in the rat subtotal nephrectomy model (Zhu et al., 2016)

Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus

Accompanying inflammation and mechanical damage, oxidative stress and multiple forms of cell death are deeply involved in the molecular mechanisms driving OA progression (15)