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These SCFAs are an energy source for colonic epithelium, liver, and peripheral tissues (243)

and, as noted above, the same medical necessity requirements are applied for POCs established with and without orders, with the exception that for those POCs established with an order, the medical reviewers may additionally look for documentation in the patient's medical record of the written order/referral and evidence that the POC was submitted to the physician/NPP within 30 days of the therapist's evaluation

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Limitations of Current Research Despite promising research demonstrating the potential benefits of BPC 157, several limitations exist