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Late stage PD is characterised by an increasing burden of drug refractory motor and non-motor symptoms with limited efficacy of available treatment options highlighting the pressing need for disease-modifying therapies

This 90-day randomized controlled trial (n=32) systematically evaluated the effects of Wuwei Jianpi San (WJPS), a traditional Chinese herbal formulation, on growth performance, immune function, gut microbiota, and bile acid metabolism in yaks, which is the first systematic association between the traditional Chinese medicine compound WJPS and the multi omics characteristics of yak intestines, aiming to address these challenges

10.3390/ijms20205199 134 YanC.LiN.XiaoT.YeX.FuL.YeY.et al (2022)

If you only have small amounts of healthy bile released from the gallbladder, bile-sensitive bacteria may become more resistant and harder to kill

2.1.2 Distribution In the plant kingdom, luteolin is commonly found in a glycosylated state