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When cells respond to chronic hyperglycemia, the expression of NOX enzymes is upregulated, activating angiotensin II type 1 receptor (AT1R) and increasing superoxide production [152153]

As compared with non-metastatic set up, LOX expression in human HCC cells was significantly enhanced in metastatic set up after interaction with polarized macrophages in vitro

T lymphocytes are a major source of cytokines

A mutation associated with Arts Syndrome, PRPS1 R196W, exhibits decreased O -GlcNAcylation levels and activity of PRPS1

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