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The onset and progression of cancer exploit gradual elevations in ROS levels

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For example, peptides help orchestrate hormone activity, immune defense, tissue repair and growth, control of inflammation, and digestion

Overall, these data support a model whereby hemeHPX could potentially interact with a plasma membrane HSPG, possibly by binding ligands and then presenting them, as suggested for LRP1, for endocytosis (Kanekiyo et al., 2011)