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This concept may be more plausible in the light of the emerging understanding of the functional matrix of the brain [for a review, see (Stam, 2014) and (Nichols et al., 2017)]

Factors affecting excitatory amino acid release following severe human head injury

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Other key metabolites include butyrate, which degrades -synuclein via the autophagy pathway involving Atg5, inhibits demyelination, enhances myelin regeneration, promotes oligodendrocyte differentiation, and protects the nervous system

doi:10.1016/j.jmoldx.2010.10.004 Preuss CV, Wood TC, Szumlanski CL, et al