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Certain pathological conditions leading to catabolic stress where intracellular glutamine levels may drop below 50% and plasma concentration below 30%, body requirement for glutamine overwhelms the capacity of body for de novo synthesis of glutamine (21), and therefore depends on dietary glutamine supplementation

Search terms included combinations of mitochondrial ROS, oxidative stress, skeletal muscle atrophy, supraspinatus, rotator cuff injury, muscle unloading, and mitochondrial dysfunction, using appropriate Boolean operators

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