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Another promising combination is using both anti-PD-1 and anti-CTLA-4 antibodies, which together enhance the immune response by reducing the number of immunosuppressive cells (MDSCs) in the TME, helping the immune system to target the tumor more effectively [74] (Fig

Moyer VA (2014) U.S

[DOI] [PubMed] [Google Scholar] 272.Muller FL, Liu Y, Van Remmen H

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