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These modifications include the following: Reducing the amount of food per meal (dividing the amount into several meals) Lose weight by practicing sports activities Avoid foods that increase heartburn (chocolate, fatty foods, caffeine, mint, garlic, onions) Quit Smoking Avoid lying down immediately after eating It is preferable to raise the head of the bed to 45 degrees while sleeping What are the causes of hiatal hernia

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Concordance (shared diagnosis) of 90% of monozygotic (identical twins) and 10% of dizygotic (fraternal twins), published in the 1970 s, was initially used to justify an intensive focus on genetics to the exclusion of environmental influence [150]

doi: 10.2174/1381612811319130011 3

Since astrocytes are closely linked with the synapse, which receives signals from the pre-synaptic neuron and responds by releasing feedback signals, they play a crucial role in brain function in health and disease