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Int J Mol Sci (2017) 18:120

27 DalakourasA.WasseneggerM.McMillanJ

Yin, N., et al

This versatility stems from the therapys ability to deliver substances directly where the body needs them most

Induction of microsomal enzymes can occur with: Biphenylles with polychlor DDT and some insecticides Benzopyrenes and other polycyclic aromatic hydrocarbons (products of burned coal and petroleum products) Polycyclic hydrocarbons in the cigarette smoke can induce some enzymes like CYP1A2 and CYP1A1 (For this reason, the metabolism rate of chlorpromazine, theophylline and imipramine is significantly high in heavy smokers)