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Biologically, benzodiazepines and Zdrugs suppress slowwave sleep and alter sleep architecture, diminishing restorative function even as total sleep time increases ( 4.4.2 COVID-19 as a dualhit stressor A history of COVID-19 infection was strongly associated with both adverse phenotypes (OR ~16 for each), highlighting a mechanism that spans biological and psychological domains

Metformin in non-alcoholic fatty liver disease: a systematic review and meta-analysis

It is the most abundant intracellular antioxidant in the body

Selective autophagy of mitochondria (mitophagy) is triggered when damaged or depolarized mitochondria accumulate PINK1 on the outer mitochondrial membrane, leading to recruitment and activation of the E3 ubiquitin ligase Parkin

The oxidative stress due to I