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Proc Natl Acad Sci 109(23):91619166 Mao CD, Hoang P, DiCorleto PE (2001) Lithium inhibits cell cycle progression and induces stabilization of p53 in bovine aortic endothelial cells

Bisulfite sequencing revealed that GEN induced methylation of a CpG island in the promoter region of Sfrp5, and this hypermethylated region overlapped with the H3Ac-depleted fragment, indicating cooperative gene repression through both DNA and histone modification (62)

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An MRI can also show bleeding at the site of a ruptured plaque