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mtDNA levels in AH serum were about two-fold lower compared to those detected in plasma, and demonstrated similar pattern of significant, but weaker associations with above clinical parameters

The safety profile of AOD-9604 is favorable compared to many metabolic interventions, with clinical trials involving approximately 900 participants demonstrating good tolerability and minimal side effects

A few (like PT-141) can be nasal

This pathological process clinically results in progressive muscle weakness and atrophy, spasticity, respiratory failure, and finally death [1]

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