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Description

In addition to anemia, patients present with jaundice (increased bilirubin), reticulocytosis, and splenomegaly

an inhibitor of GCL and consequently of glutathione synthesis) enhanced ferroptotic cell death induced by all ferroptosis-inducing compounds, and its modulation effect is specific to ferroptosis-inducing compounds

This work was supported by the Japan Society for the Promotion of Science (JSPS) Grant-in-Aid for Young Scientists (B) Grant Number JP15K19036 (SH), JSPS Grant-in-Aid for Young Scientists Grant Number JP19K16271 (SH), Japan Science and Technology Agency (JST) ACT-X Grant Number JPMJAX201A (SH), RIKEN FY2018 Incentive Research Projects (SH), and Naito Grant for female scientists after maternity leave (SH)