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These include members of the transient receptor potential (TRP) channel superfamily, which mediate extracellular calcium influx in response to hormonal and environmental cues, and store-operated calcium entry (SOCE) channels, such as the STIM1-ORAI1 complex, which replenish intracellular calcium stores following depletion [31]

Contrast-enhanced MRI found, having administered bevacizumab, that spreading gliomas had a non-enhancing pastern consistent with invasive perivascular malignant progression [40,20]