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Phase Washout Duration 1-3 weeks Daily Dose 0 mcg Notes Rest period before repeating the course

Serious systemic reactions: rare but possible Reports exist of anaphylaxis and severe allergic responses after vitamin B12 injections

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Many studies have proven the efficacy of restricted radiation areas on reduced gastrointestinal side effects as well as enhanced dose tolerance in radiotherapy ( b) Dose-Volume Effect Radiation-induced digestive injury manifests as a dose-volume effect, meaning that the extent of the lesion highly depends on the radiation dose and radiated volume (3443) and precisely predicted (44)