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Multiple protective functions of catalase against intercellular apoptosis-inducing ROS signaling of human tumor cells

doi: 10.1073/pnas.1612920114 346 O'CallaghanGRyanANearyPO'MahonyCShanahanFHoustonA

Notably, splenectomy is associated with a 4-fold increase in thrombosis risk in transfusion-dependent thalassemia, potentially exacerbated by hyperhomocysteinemia and oxidative endothelial damage [10].The interplay between homocysteine and oxidative stress in thalassemia appears to be complex