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251 Various PI3K inhibitors are currently being used in clinical trials, primarily for malignant tumours

Seo et al., 2016

Our approach combines the physicochemical properties of amino acids in the peptide which favour T-cell receptor (TCR) binding along with factors important for antigen presentation and processing (expression of the mutant gene in the tumour, HLA type, HLA binding affinity and proteasomal cleavage and processing of the peptide)

In the recent past, a growing body of scientific research has begun to shed light on the critical involvement of the neuro-immune axis in the onset and advancement of these debilitating conditions