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Consistent with the results acquired from PC cell lines, PDCs with low expression of VRK2 were more sensitive to APR-017 treatment than PDCs with high expression of VRK2 (Fig

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These results indicate that the substrate specificity of the latter differs fundamentally from that of its non-mammalian homologs

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PMID: 12201498

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5-HTP: May deplete dopamine levels, which can interfere with barrier recovery and mental health

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