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This signals them to start producing collagen and elastin, with new cells replacing older ones

Microbial biotransformation produces a wide range of BA species, where even minor structural changes can lead to differential receptor engagement and functional consequences (163)

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In yeast, retrograde transport is mediated by the retromer complex, a pentamer composed of a membrane-binding SNX subcomplex, formed by the heterodimer Vps5p and Vps17p, and a cargo-recognition VPS subcomplex comprising Vps26p, Vps29p, and Vps35p 26

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