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SDMA repeated measurements over time, as recommended by IRIS guidelines, are necessary, because one determination does not allow us to exclude definitely a later onset of the renal impairment and then to be considered diagnostic in order to highlight a possible onset of CRS [cardiorenal syndrome]." In a September 2021 article, Italian researchers studied 85 MVD-affected dogs, including 9 (9.3%) cavaliers, to measure the plasma concentration of dimethylarginines in the various stages of MVD

Evolving concepts in the pathogenesis of uraemic cardiomyopathy

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