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In addition to the technical and regulatory hurdles, there are also clinical application challenges associated with the use of CeO 2 NPs in wound healing therapies

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Table IV [i] MASLD metabolic dysfunction-associated steatotic liver disease, TNF- tumor necrosis factor-, IL interleukin, CRP C-reactive protein, CCL2 C-C motif chemokine ligand 2, MCP-1 monocyte chemoattractant protein-1, CXCL10 C-X-C motif chemokine ligand 10, ICAM-1 intercellular adhesion molecule 1

For autoimmune patients who also have metabolic syndrome, these changes address a significant contributor to their overall inflammatory burden