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We hypothesized that cromolyn, a mast cell stabilizer that prevents the release of inflammatory mediators, would decrease peripheral and central inflammation, reduce MC trafficking to the brain, and improve stroke outcomes

SAM originated from methionine cycle in which 5-methyl THF transfers methyl groups to homocysteine in a reaction catalyzed by methionine synthase to produce methionine

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Participants administered a mean chlorpromazine equivalent dose of 592.84 164.90 mg/day and a lorazepam equivalent dose of 1.58 0.70 mg/day